It has two clinicopathologic variants, namely intraosseous follicular and. Adenomatoid tumors of the scrotum are benign, solid extratesticular lesions that can originate from the epididymis, tunica vaginalis, or spermatic cord 90% derived from the funiculus. Introduction the adenomatoid odontogenic tumour aot is a benign, hamartomatous lesion of odontogenic epithelial origin1. This article describes a case of extrafollicular adenomatoid odontogenic tumor in a yearold male, located in the maxilla treated by enucleation.
May cause migration of teeth adenomatoid odontogenic tumor. Even though there is evidence that tumor cells originate from the epithelium of the tooths enamel, it has been suggested that this lesion originates from dental lamina remnants. Extrafollicular adenomatoid odontogenic tumour bmj case. It is well known for its unique histopathologic features, predilection for young individuals, and innocuous behavior. In your practices and in the board exams when they inform you. The tumor which today is called adenomatoid odontogenic tumor aot was probably first described by dreibladt 1907, quoted in thoma 1970, who called the tumor pseudoadenoma adamantinum, and then by harbitz 1915, who called it adamantine cystadenoma gorlin and goldman 1970. When they occur outside the genital region, they may involve the following sites. A possible differential diagnosis for the lesion described in this case report is a dentigerous cyst and an adenomatoid odontogenic tumor.
Clinical statistics of the adenomatoid odontogenic tumour. Adenomatoid odontogenic tumor aot is a relatively uncommon odontogenic tumor characterized by the formation of ductlike structures by the epithelial component of the lesion. View enhanced pdf access article on wiley online library html view. Adenomatoid odontogenic tumor aot is an uncommon tumor of odontogenic origin. The aim of this study was to determine the biologic profile of the adenomatoid odontogenic tumor aot in a thai population. Adenomatoid odontogenic tumor case report case report vol. Adenomatoid odontogenic tumor aot is a rare odontogenic tumor which is often misdiagnosed as odontogenic cyst. Adenomatoid odontogenic tumor associated with an impacted. Adenomatoid odontogenic tumor constitutes an uncommon benign odontogenic tumor which is wellknown as twothirds tumor twothirds of adenomatoid tumors occur in the maxilla, twothirds occur in young females, twothirds of the cases are associated with unerupted teeth and twothirds of the affected teeth are canines. Both dentigerous cyst and adenomatoid odontogenic tumors are entirely benign, encapsulated lesions, and enucleation poses no major difficulties.
Adenomatoid odontogenic tumors, fenestration decompression, enucleation introduction adenomatoid odontogenic tumors aot are exceptionally rare and benign, originating in the odontogenic epithelium and accounting for 2. They are the most common extratesticular neoplasm, and most common tumor of the epididymis, and occur more often in the lower pole than in the upper pole by a. Immunohistochemical demonstration of an enamel sheath protein, sheatlin, in odontogenic tumors. Introduction adenomatoid odontogenic tumor aot is an uncommon, benign epithelial lesion of odontogenic origin, representing approximately 3% of all odontogenic tumors 1. It is slow growing, occurs twice as common in females and usually in the second decade of life. Extrafollicular adenomatoid odontogenic tumor a case report thomas ninan, nishath khanum, prathibha rani rm and srisha basappa oral medicine and radiology, farooqia dental college and hospital, mysore, india case report abstract the adenomatoid odontogenic tumor aot is a benign, nonneoplastic lesion with a slow but progressive growth.
Ameloblastomas and adenomatoid odontogenic tumors aots are common epithelial tumors of odontogenic origin. Only about 750 cases have been reported in scientific literature. Numbers at the top and bottom of the lines indicate cases involving both adjoining regions. The large majority of odontogenic tumors occur within the maxillofacial skeleton. Extrafollicular adenomatoid odontogenic tumor a case. Adenomatoid odontogenic tumor aot is a benign neoplasm of odontogenic epithelium. Assessment of mri and dynamic contrastenhanced mri in the.
We attempted to differentiate aot from other lesions similar to aot in radiographic findings using mri. The patient is in postoperative followup, without any clinical and radiographic signs of lesion recurrence. Topographical distribution of the known precise locations n 646 of follicular adenomatoid odontogenic tumors aots. Peripheral adenomatoid odontogenic tumor in a cloak of an.
Adenomatoid tumors of the scrotum radiology reference. Two thirds of the cases are associated with an impacted tooth usually being the canine. Adenomatoid odontogenic tumor is a hamartomous benign neoplasia of odontogenic origin. Adenomatoid odontogenic tumour aot is an uncommon, benign tumour that represents 37% of all odontogenic tumours. We report two cases of an exceptional combination of these tumors with either an ameloblastic fibroodontoma or an odontoma. Immunohistochemical demonstration of bone morphogenic protein in odontogenic tumors. Since its first description by ghosh in 1934, more than 160verifiable caseshave been reported worldwide115. Adenomatoid odontogenic tumor definition of adenomatoid. It appears as a radiolucent lesion with smokey dense areas. Odontogenic tumor an overview sciencedirect topics. It is a relatively uncommon neoplasm that accounts for about 3% of all odontogenic tumors being more. Several tumors exist, which only appear to occur in the jaws. A well circumscribed lesion derived from odontogenic epithelium that usually occurs around the crowns of unerupted anterior teeth of young patients and consists of epithelium in swirls and ductal patterns interspersed with spherical calcifications. There is some variation in nuclear size and shape, but this is not a malignant tumor.
However, adenomatoid odontogenic tumor occurs mostly in the anterior maxillary region and is associated in 60% of cases with a canine 3, 10, 14, 15. The adenomatoid odontogenic tumor aot is usually an asymptomatic slow growth lesion. If the dental follicle is found to be uninvolved during surgery and if it can be easily separated from the tumor, it may be possible to remove the lesion while leaving the teeth in place. Conservative surgical excision is the treatment of choice. Abstract adenomatoid odontogenic tumor aota benign hamartomatous lesion of odontogenic origin, is an uncommon tumor which affects mainly females in the second decade. Adenomatoid odontogenic tumor aot is an uncommon benign odontogenic lesion that affects young patients associated with an impacted tooth, usually canine. It is termed as aot in short and represents 3% to 7% of all odontogenic tumors. The adenomatoid odontogenic tumor is an odontogenic tumor arising from the enamel organ or dental lamina. Calcifying epithelial odontogenic tumors ceots and calcifying odontogenic cysts cocs are rare, benign odontogenic tumors. Aot is mostly infrequent, benign neoplasm and organizes around 7% of all tumors of odontogenic origin. Adenomatoid odontogenic tumors represent 3 to 7% of all odontogenic tumors. It is common for the tumor to cause shifting of neighboring teeth because tumor expansion is more common than teeth root resorption. In the past, this tumor has been referred to as adenoameloblastoma or ameloblastic adenomatoid tumor. A series of four clinicopathological variants namrata n patil, abhishek singh nayyar, vijay wadhwan.
Adenomatoid odontogenic tumor with features of calcifying epithelial odontogenic tumor. There are three subclinical types of this tumour with identical histology. Introduction a cyst is an epithelium lined sac containing fluid or semifluid material the epithelial cells first proliferate and later undergo degeneration and liquefaction grow by. Adenomatoid odontogenic tumor aot is a benign lesion from the dental lamina or its remains. Adenomatoid odontogenic tumor aot is a benign lesion from the dental lamina or its. Adenomatoid odontogenic tumors are rare and differ from most other dentition related lesions in that they more frequently occur in the maxilla. When grown, one can palpate a hard and large lesion.
Ranking four among the odontogenic tumors the aot is not a particularly rare tumor. Adenomatoid odontogenic tumor aot is a distinct odontogenic tumor that is exclusively odontogenic epithelium in origin which accounts for about 37% of all odontogenic tumors. Overall, odontogenic tumors are rare and form only a small proportion of the lesions found in the jaw. Study on the origin and nature of the adenomatoid odontogenic tumor by immunohistochemistry. Adenomatoid odontogenic tumor is also called twothirds tumor, because 23 rd occur in young females, 23 of adenomatoid tumors occur in the maxilla, 23rd of the cases are associated with unerupted teeth, and twothirds of the affected teeth are canines. The radiographical differentiation of adenomatoid odontogenic tumor aot from dentigerous cysts, calcifying odontogenic cysts, calcifying epithelial odontogenic tumors, odontogenic keratocysts and amelobastomas is sometimes difficult.
Case 3 the adenomatoid odontogenic tumor aot is usually an asymptomatic slow growth lesion. Females are more commonly affected than males with a ratio of 2. It is a benign hamartomatous, noninvasive lesion with slow but progressive growth. Adenomatoid odontogenic tumor aot is a rare tumor of epithelial origin comprising 3% of all the odontogenic tumors. Adenomatoid odontogenictumourjawelinicalstatistics. Adenomatoid odontogenic tumor aot is considered as a benign, nonneoplastic hamartomatous tumor, with a slowly progressing growth. Sixtyseven cases of aot registered from january 1974 to may 2006 were studied retrospectively. Adenomatoid odontogenic tumor aot is a slow growing, benign. It is predominantly found in young and female patients, located more often in the. Adenomatoid tumor of peritoneum smooth transparent serous membrane lining the internal abdominal cavity adenomatoid tumor of pleura the membrane lining the lungs. Epidemiology they are also seen more frequently in females, most frequently in the second decade of.
This is an adenomatoid tumor, which is of mesothelial origin as the staining pattern suggests. Note the ductlike structures see arrow odontogenic tumors. It is considered as a hamartoma rather than a true neoplasm because of slow growth and circumscription of the lesion. A, e multiple epithelial follicles with calcifications arrows. Aot accounts for about 1% until 9% of all odontogenic tumors. Clinical features of most benign odontogenic tumors are nonspecific. Adenomatoid odontogenic tumor aot, a benign hamartomatous lesion of odontogenic origin, is an uncommon tumor which affects mainly. They sometimes raise a significant diagnosis and therapeutic challenge, comparatively with previously described lesions. Adenomatoid odontogenic tumor was formerly considered to be a variant of aneloblastoma and was called as adenoamelobalstoma. Adenomatoid odontogenic tumor histological, radiological. Although they do not normally contain odontogenic tissue, they are probably odontogenic because of their site of origin. Adenomatoid tumors rarely involve the testicular parenchyma and are the most common paratesticular tumor. The patient presentation of a small painless mass in a patient in the third fourth decade is typical. Aot and the ameloblastic fibroma are odontogenic tumors of young people.
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